A crosssectional study was conducted in 13 wards of Morogoro municipality,Tanzania, from October 2014 to January 2015 , to assess possible health risks associated with urban and peri-urban pig production and identify available biosecurity measures. A total of 282 pig farmers were randomly chosen from purposively selected streets were interviewed using a structural questionnaire to measure respondents’ knowledge on the diseases that have affected his/her pigs. The survey also assessed husbandry systems and practises, animal waste management as well as biosecurity measures pratcised by pig farmers. Twelve key informants were interviewed on the subject; qualitative data were subjected to content analysis and association between variables were assessed for statistical significance at a critical probability of P <0.05. Data from questionnaire were analysed using the Statistical Package for Social Sciences (SPSS). The study revealed that 48.6% of respondents were not aware of health risks associated with pig production. Approximately 9.2% reported to wear local protective gears (wrapping plastic bags on hands and local shoes known as Yeboyebo) while 19.1% did not have any protective gears. Only 0.4% generated biogas out of the manure. Animal quarantining was practised by 68.4%, presence of screening was 20.6%, while veterinary service was accessible to 66.3% of the farmers interviewed. Poor animal wastes disposal is becoming a major challenge to public health. Farmers should be advised and trained to generate biogas out of the manure, livestock officers should be supported with transport to ensure timely delivery of veterinary services to all the livestock keepers especially those who reside at the peripheral areas.